The average CRNA salary in South Carolina is $217/hr or approximately $250k per year. Locum tenens CRNAs in South Carolina earn significantly more — typically $282–$391/hr, or 30–80% above permanent rates. CRNAs in South Carolina practice under physician supervision or a collaborative agreement. RxRooster aggregates CRNA salary data and job listings from 20+ sources across South Carolina.
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CRNA Salary in South Carolina
Compensation data for Certified Registered Nurse Anesthetists in South Carolina (2026).
$217
Permanent hourly
$282–$391
Locum hourly
$250k
Annual salary
What affects CRNA pay in South Carolina?
Practice authority
South Carolina requires physician supervision. CRNAs may see slightly lower autonomy premiums than FPA states.
State tax
South Carolina collects state income tax. Consider effective take-home when comparing to no-tax states.
Locum vs. permanent
Locum CRNAs in South Carolina commonly earn $282–$391/hr, 30–80% above permanent staff rates.
Facility type
Level-I trauma and academic centers pay differently than community hospitals or outpatient surgery centers. Compare offers on RxRooster.